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Updated: Sep 9, 2025

A Model of Reverse Vascular Remodeling in Pulmonary Hypertension Due to Left Heart Disease by Aortic Debanding in Rats
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Published on: March 1, 2022

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在肺动脉高血压中参与血管改造的生长因子

Aya Yamamura1

  • 1Department of Physiology, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi 480-1195, Japan.

Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi
|September 3, 2025
PubMed
概括

通过促进肺动脉光滑肌细胞的增殖,血小板衍生生长因子 (PDGF) 驱动肺动脉高血压 (PAH). 用伊马替尼或冠状酸抑制PDGF信号,减少了细胞生长,改善了大鼠的血管重塑.

关键词:
增长因子扩散肺高血压滑动肌肉血管改造

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