危急儿童的维生素C度低和预后
Min Jung Kim1, Yoon Hee Kim2, Soo Yeon Kim3
1Department of Pediatrics, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Korea.
Acute and critical care
|September 3, 2025
概括
重症儿童的维生素C缺乏与更长的住院时间和炎症增加有关. 补充剂可能对这些患者有好处.
科学领域:
- 儿童重症监护医疗
- 营养生物化学
背景情况:
- 高剂量的维生素作为危急病患者的辅助疗法正在研究中.
- 血清维生素C与重症儿童的预后之间的关联需要评估.
研究的目的:
- 评估血清维生素C度与儿科重症监护室 (PICU) 患者预后之间的关联.
主要方法:
- 对63名进入PICU的儿童的临床和生化数据进行了回顾.
- 分析包括胺和维生素C水平,停留时间,机械通风持续时间和炎症标志物.
主要成果:
- 维生素C缺乏 (27. 0%) 与较长的PICU停留和机械通风持续时间有关.
- 在维生素C缺乏症患者中观察到炎症标志物 (三角中性粒细胞指数,C反应蛋白,乳酸) 的升高.
- 维生素C水平受营养状况的影响,没有基于PICU入院原因的差异.
结论:
- 维生素C缺乏与严重疾病儿童的炎症增加和呼吸时间延长有关.
- 结果表明,维生素C在这种患者群体中具有潜在的益处.
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