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Updated: Sep 9, 2025

Single-Cell Resolution Three-Dimensional Imaging of Intact Organoids
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Single-Cell Resolution Three-Dimensional Imaging of Intact Organoids

Published on: June 5, 2020

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在完整的活组织中进行单细胞分辨率的3D成像和细分

Giulia Paci1,2, Pablo Vicente-Munuera3,4, Inés Fernandez-Mosquera5,6

  • 1Laboratory for Molecular Cell Biology, University College London, London, UK. g.paci@ucl.ac.uk.

Npj imaging
|September 3, 2025
PubMed
概括

这项研究介绍了Drosophila翅膀盘中的3D成像和基于深度学习的细胞细分方案. 它可以准确量化活组织中的细胞结构,用于生物研究.

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Three-Dimensional Microscopy in Microbiology01:28

Three-Dimensional Microscopy in Microbiology

Three-dimensional imaging techniques are essential in cell biology, allowing researchers to visualize intricate cellular structures with high resolution. Two prominent methods, Differential Interference Contrast Microscopy (DIC) and Confocal Scanning Laser Microscopy (CSLM), provide distinct advantages for imaging live and thick specimens, respectively.Differential Interference Contrast MicroscopyDIC microscopy enhances contrast in transparent, unstained samples by converting phase...
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