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Updated: Sep 9, 2025

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
07:06

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对性结肠炎的IBD-DCA的实施:一个机构的经验

David Egong1, Michéal Hanly2, Erinn McGrath3

  • 1Department of Pathology and Laboratory Medicine, St Vincent's University Hospital, Dublin, Ireland. david.egong@icloud.com.

Virchows Archiv : an international journal of pathology
|September 3, 2025
PubMed
概括

炎症性肠病分布,慢性,活动 (IBD-DCA) 评分系统在性结肠炎 (UC) 活检中被广泛采用. 组织学活性与内学严重性相关,有助于临床试验应用.

关键词:
在IBD-DCA欧盟国家安全委员会大肠炎

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Ulcerative colitis is a chronic inflammatory condition primarily affecting the colon and rectum. The primary drugs used in the treatment of ulcerative colitis are aminosalicylates. They exhibit anti-inflammatory and immunosuppressive properties. They modulate inflammatory mediators and inhibit the activity of nuclear factor κB (NF-κB). Aminosalicylates also reduce inflammation by inhibiting prostaglandin and leukotriene production and decreasing neutrophil chemotaxis and superoxide...
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Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
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The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Glucocorticoids, a class of anti-inflammatory drugs, are pivotal in treating moderate to severe Crohn's disease by inducing remission. They exhibit their anti-inflammatory action by inhibiting the production of inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1, and chemokines like IL-8. In addition, they reduce the expression of inflammatory cell adhesion molecules and inhibit gene transcription of nitric oxide synthase, phospholipase A2, cyclooxygenase-2...
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