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Updated: Apr 28, 2026

Construction and Implantation of a Microinfusion System for Sustained Delivery of Neuroactive Agents.
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Construction and Implantation of a Microinfusion System for Sustained Delivery of Neuroactive Agents.

Published on: March 17, 2008

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持续释放的3D打印加巴丁装载植入物:利用3D打印和热挤出 (HME) 进行可定制的药物输送

Baher A Daihom1,2,3, Hala M Abdelhakk1,4, Mohammed Maniruzzaman5,6

  • 1Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, The University of Texas at Austin, Austin, TX, 78712, USA.

AAPS PharmSciTech
|September 3, 2025
PubMed
概括

这项研究开发了3D打印的聚氨酸植入物,用于治疗儿童神经病痛的持续释放 gabapentin. 优化3D打印实现了药物输送的控制,

关键词:
三维打印加巴丁的使用情况热挤出植入物真空压缩建模

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Microgel-Extracellular Matrix Composite Support for the Embedded 3D Printing of Human Neural Constructs07:48

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相关概念视频

Modified-Release Drug Delivery Systems: Rate-Programmed II01:19

Modified-Release Drug Delivery Systems: Rate-Programmed II

Rate-programmed drug delivery systems release drugs in a controlled manner to maintain therapeutic levels. Three main designs include reservoir, matrix, and hybrid systems.Reservoir systems consist of a drug core enclosed within a membrane that controls drug release. In non-swelling reservoir systems, polymers like ethyl cellulose or polymethacrylates are used. These do not hydrate in aqueous media and control release through membrane thickness, porosity, or insolubility. This type includes...
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