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A Proinflammatory, Degenerative Organ Culture Model to Simulate Early-Stage Intervertebral Disc Disease.
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生物活性丝纤维素水凝套装BMSCs-EVs调节椎间盘退化中的炎症微环境

Qi Liu1, Jiaying Luo2, Huan Wang1

  • 1Department of Orthopedics, Shengjing Hospital of China Medical University, Shenyang, China.

Journal of extracellular vesicles
|September 4, 2025
PubMed
概括

这项研究开发了一种带有工程外细胞囊的丝纤维蛋白水凝,用于治疗椎间盘退化 (IVDD). 这种疗法调节了巨细胞的两极分化,减少了炎症,并促进了磁盘的再生.

关键词:
骨髓介质干细胞衍生的细胞外囊椎间盘退化mRNA 修改巨细胞的两极化丝纤维素水凝转录组分析

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