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Updated: Sep 9, 2025

Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice
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关于C57BL/6和BALB/c小鼠亚株的表型和遗传差异的简要介绍

Lan Zhao1,2, Jie Wei1,2, Bingfei Yue1,2

  • 1Division of Laboratory Animal Monitoring, National Institutes for Food and Drug Control, Beijing, China.

Animal models and experimental medicine
|September 4, 2025
PubMed
概括

了解像C57BL/6和BALB/c这样的小鼠亚株对于可靠的生物医学研究至关重要. 这篇评论详细介绍了它们的遗传和表型差异,有助于进行最佳的实验选择.

关键词:
BALB/c小鼠在C57BL/6小鼠遗传上的差异表型上的差异亚菌株

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Background and Environment Affect Phenotype

Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
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