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Updated: Sep 9, 2025

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一个分子开关将大脑健康与神经退行联系起来

Nan Shao1, Xiaoyan Zhang2, Yunzhi Ge1

  • 1College of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, Anhui Province, China.

Neural regeneration research
|September 4, 2025
PubMed
概括

与O结合的N-乙糖胺 (O-GlcNAc) 修饰对于大脑健康,调节蛋白质和细胞信号至关重要. 在O-GlcNAc的不平衡有助于神经退行性疾病,但针对这个途径提供治疗潜力.

关键词:
阿尔茨海默病亨廷顿病一个小小的案例与O结合的N-乙糖胺与O结合的N-乙糖胺转移酶帕金森病肌缩侧面硬化症六胺生物合成途径神经再生神经退行症神经元功能

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