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Updated: Jul 5, 2026

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Nicholas Sweeney1, Tae Yeon Kim1,2, Hongjun Fu1,3

  • 1Department of Neuroscience, College of Medicine, The Ohio State University, Columbus, OH, USA (Sweeney N, Kim TY, Fu H).

Neural regeneration research
|September 4, 2025
PubMed
概括

No abstract available in PubMed .

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Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...