获得帕金森病深度脑刺激手术的种族和性别差异
Fang Ba1, Sabrina Pooja1, Pouria Torabi1
1Division of Neurology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Movement disorders clinical practice
|September 4, 2025
概括
在加拿大,深度大脑刺激 (DBS) 对于帕金森病的治疗未能得到充分的应用. 这项研究发现了显著的种族和性别差异,受过教育的白人男性在DBS治疗中占比过高.
科学领域:
- 神经学
- 神经外科
- 医疗服务研究
背景情况:
- 深度脑刺激 (DBS) 是帕金森病 (PD) 的关键治疗方法.
- 在加拿大的女性和种族群体中潜在的DBS使用不足需要调查.
- 影响这些人群获得DBS的障碍和偏见尚不清楚.
研究的目的:
- 确定转诊和接受DBS的患者之间的性别,种族和人口统计差异.
- 将DBS候选人的人口特征与加拿大普通人口进行比较.
主要方法:
- 来自加拿大两家中心和加拿大开放帕金森网络 (C-OPN) 的DBS患者的回顾性图表和电话调查.
- 对包括性别,种族,婚姻状况,母语,出生国,居住地,教育,收入和转介来源在内的人口因素进行分析.
主要成果:
- 与女性相比,男性更常被转诊并接受DBS治疗.
- 大多数患者为白人 (81. 8 - 94. 1%),不代表加拿大人口统计学.
- 接受DBS治疗的患者受教育程度较高,并且比一般人群更有可能结婚.
结论:
- 在加拿大,在帕金森病的DBS中存在显著的种族和性别差异.
- 在DBS患者群中受过教育的白人男性占比过高.
- 所有符合条件的PD患者,包括妇女和种族群体,都需要平等地获得DBS.
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