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Updated: Sep 9, 2025

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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在真菌中揭示III型多基合成酶的功能多样性

Nika Sokolova1, Stepan S Denisov2, Thomas Hackl3

  • 1Department of Chemical and Pharmaceutical Biology, University of Groningen, Antonius Deusinglaan 1, Groningen, 9713AV, The Netherlands.

Angewandte Chemie (International ed. in English)
|September 4, 2025
PubMed
概括

我们开发了一种新方法来描述真菌III型多基合成酶 (T3PKS), 发现了新的酶特异性, 并创建了一个用于预测其活性的机器学习模型.

关键词:
生物催化菌类基因组挖掘机器学习多种类型

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