呈现同步胃转移的三阴性侵袭性叶状癌:病例报告
Liangxue Zhu1, Yajun Xing1, Mingyun Wang1
1Department of Oncology, Nanjing Gaochun People's Hospital, Jiangsu, Nanjing 211300, P.R. China.
Oncology letters
|September 4, 2025
概括
这份病例报告详细介绍了一例罕见的三阴性侵袭性叶状癌 (TN-ILC),在初始诊断时出现了胃转移. 这突显了转移性乳腺癌的彻底评估的重要性,即使没有胃肠道症状.
科学领域:
- 癌症学
- 病理学
- 放射学
背景情况:
- 三阴性侵袭性叶状癌 (TN-ILC) 是一种罕见的侵袭性乳腺癌亚型.
- 乳腺癌的胃转移非常罕见,通常在诊断后几年出现.
研究的目的:
- 在初始诊断时报告同步胃转移的单一TN-ILC病例.
- 强调这种罕见病例的诊断挑战和全面评估的必要性.
主要方法:
- 一个68岁的绝经后女性的病例报告.
- 使用成像 (例如CT,MRI) 和组织病理学分析.
- 通过免疫组织化学证实TN-ILC和转移性传播 (GATA3,Villin,CK7/20).
主要成果:
- 患者被诊断为TN-ILC (ER-, PR-, HER2 1+) 扩散转移包括胃,大脑,骨,上腺,上腺和淋巴结.
- 胃转移模仿了原发性胃癌, 造成了诊断上的挑战.
- 患者没有报告最初的胃肠道症状.
结论:
- 这一案例突显了TN-ILC在初始诊断时出现胃转移的罕见情况.
- 对于转移性乳腺癌来说,全面的诊断工作至关重要,以避免误诊,特别是当转移模仿原发性瘤时.
- 在这种情况下,胃肠道症状的缺失强调了评估转移模式时需要保持警.
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