空气污染和破坏的微生物组:追踪对人类健康的影响
Treesa Thomas1, Abdulqadir J Nashwan1
1Nursing and Midwifery Research Department, Hamad Medical Corporation, Doha, QAT.
Cureus
|September 4, 2025
概括
空气污染显著改变肠道微生物,影响整体健康. 益生菌和饮食等保护措施可以减轻这些影响, 但长期暴露会带来风险,
科学领域:
- 环境健康科学
- 微生物组研究
- 毒理学
背景情况:
- 空气污染是众所周知的各种疾病的危险因素.
- 新出现的证据将空气污染物与肠道微生物群的变化联系在一起.
- 肠道微生物群在维持人类健康方面起着至关重要的作用.
研究的目的:
- 对空气污染对肠道微生物群的影响进行现有文献的范围审查.
- 综合有关空气污染引起的肠道疾病的健康后果的发现.
- 确定潜在的减缓策略和知识差距.
主要方法:
- 在PubMed和Scopus数据库中进行全面的文献搜索.
- 对159篇选定的论文进行了深入分析.
- 审查的重点是2010年至2025年间发表的研究,研究了PM2.5,重金属和VOC等特定污染物.
主要成果:
- 空气污染会改变肠道微生物组成,影响呼吸,神经,心血管和新陈代谢健康.
- 肠-肺和肠-大脑轴是这些效应的关键媒介.
- 益生菌,共生菌和饮食改变显示了缓解的潜力.
结论:
- 早期和长期暴露于空气污染会对健康产生持久影响,特别是在儿童身上.
- 空气污染引起的肠道微生物群变化可能会加剧现有的疾病.
- 需要进一步研究以了解机制和公共卫生影响.
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