阿根廷缺血性中风的年轻人:全国多中心回顾性注册分析 (JACARANDA)
Fabio M Maximiliano Gonzalez1,2, Juan Ignacio Lopez3, Flavia Tamagnini4
1Hospital Británico.
概括
阿根廷的年轻人患有缺血性中风, 高血压和吸烟是主要的风险因素. 尽管最初的症状很轻微,但在90天内出现严重的残疾和死亡,这凸显了需要更好的诊断方法.
科学领域:
- 神经学
- 公共卫生
- 流行病学
背景情况:
- 年轻成年人 (18-50岁) 占缺血性中风病例的很大一部分,但拉丁美洲的数据有限.
- 了解这一群体中风的具体特征和结果对于制定有效的公共卫生策略和干预措施至关重要.
研究的目的:
- 描述阿根廷年轻人缺血性中风的人口结构,血管风险因素,中风病因和治疗机会.
- 评估90天的功能结果,包括依赖,复发和死亡率.
主要方法:
- 从2015年1月到2023年12月,在阿根廷26个中心进行了回顾性多中心队列研究.
- 包括18至50岁连续诊断患有缺血性中风的患者,分析人口统计,风险因素,中风类型和再输血治疗.
主要成果:
- 在18934名缺血性中风患者中,7. 5% (1422) 是年轻人 (中位数为43岁).
- 高血压 (31.0%),吸烟 (29.3%) 和肥胖 (18.8%) 是最常见的危险因素. 在50. 4%的病例中,病因仍未确定.
- 90天后,12. 1% 的患者出现功能依赖,3. 9% 的患者出现中风复发,4. 8% 的患者死亡.
结论:
- 在阿根廷, 缺血性中风在年轻人中是一个值得注意的问题, 几乎占13例中的1例.
- 尽管中风患者往往表现出较轻微的症状, 但他们面临着严重的残疾和死亡风险.
- 高比例的未确定的中风病因强调需要标准化的诊断方案来更好地管理和预防中风.
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