精液囊中的偶发性囊瘤:一个机构系列
Sabina Desar1, Selvaraj Muthusamy1, Alexander P Kenigsberg2
1Department of Pathology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
International journal of surgical pathology
|September 4, 2025
概括
精液囊细胞瘤,罕见的瘤,可能更常见的小,偶然的发现. 需要进一步研究以了解这些良性瘤上皮质异常的发生率和重要性.
科学领域:
- 尿道病理学
- 外科病理学
- 癌症学
背景情况:
- 精液囊细胞瘤是一种罕见的良性上皮瘤,以纤维肌层内的囊为特征.
- 传统上,这些瘤与大量效应导致的阻塞性尿路症状有关,通常在案例研究中报告.
- 事观察表明可能存在较小,偶然的呈现,可能未被充分认识到.
研究的目的:
- 研究精液囊细胞瘤的现象, 呈现为较小, 偶然的病变.
- 对精液囊中的偶发细胞瘤进行审查.
- 评估偶然发现的精液囊细胞瘤的特征和患病率.
主要方法:
- 实验室中精液囊细胞瘤病例的回顾.
- 在前列腺切除术或其他恶性瘤中偶然发现的病变的识别.
- 分析患者的人口结构,病变大小,成像检测结果 (多参数核磁共振),以及包括PAX8表达和上皮异常在内的组织病理特征.
主要成果:
- 鉴定出7种偶发性精液囊细胞瘤,大小在0. 5至1. 8厘米之间.
- 两个病例涉及双侧精液囊,其中一个同时患有前列腺囊瘤.
- 在手术前通过多参数核磁共振检测出两种病变; 一种病例显示焦点上皮质异位 (低度形); 所有病例都表达了核PAX8.
结论:
- 精液囊细胞瘤可能未被识别,经常呈现为较小,偶然的发现,而不是症状质量.
- 需要进一步的研究来确定这些偶然形式的实际患病率.
- 需要进行额外的研究来评估在精液囊细胞瘤上表皮性异常的临床意义和影响.
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