糖尿病足患者的大型截肢的发生率和原因:一项回顾性研究的数据
Marco Meloni1,2,3, Luigi Uccioli4, Aikaterini Andreadi5,6
1Department of Systems of Medicine, University of Tor Vergata, Rome, 00133, Italy. meloni.marco@libero.it.
Acta diabetologica
|September 4, 2025
概括
一个多学科糖尿病足团队 (MDFT) 在糖尿病足综合征患者中实现了非常低的2. 4%的重大截肢率. 周围动脉疾病 (PAD) 是这一群体中截肢的主要原因.
科学领域:
- 内分泌学
- 血管外科
- 传染性疾病
背景情况:
- 糖尿病足综合征是一个很大的挑战,
- 有效的管理需要一个全面的,多学科的肢体救援方法.
研究的目的:
- 确定糖尿病足综合征患者的大型截肢的发生率和病因因素.
- 评估由多学科糖尿病足团队 (MDFT) 管理的肢体救援方案的有效性.
主要方法:
- 在2020年1月至2023年11月期间因糖尿病足部问题住院的1226名患者的回顾性观察研究.
- 根据MDFT预先设定的肢体救援协议管理的患者.
- 一年后跟踪评估主要截肢率,患者特征和原因.
主要成果:
- 共有30名患者 (2. 4%) 经历了严重的截肢.
- 截肢者经常患有2型糖尿病,长时间的疾病,以及包括外周动脉疾病 (PAD),心脏疾病和脏疾病在内的多种并发症.
- 不能治愈的四肢缺血症 (56. 7%),骨骨髓炎/ 死性筋膜炎 (16. 7%) 和骨髓炎 (10%) 是主要的原因.
结论:
- 这种MDFT方法导致了很低的重大截肢率.
- 在高危人群中, 周围动脉疾病 (PAD) 成为主要的截肢病因.
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