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Updated: Sep 9, 2025

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells
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在黑色素瘤细胞表型切换中ARHGAP29的新兴作用

Beatrice Charlotte Tröster1, Melanie Kappelmann-Fenzl1,2, Anja Katrin Bosserhoff1,3,4

  • 1Institute of Biochemistry, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Erlangen, Germany.

Molecular oncology
|September 4, 2025
PubMed
概括

通过调节RhoA/ ROCK通路和细胞可塑性,促进黑色素瘤细胞的侵入. 这项研究确定ARHGAP29是黑色素瘤进展的关键驱动因素和潜在的治疗点.

关键词:
亚尔赫加普29提供RhoA/ROCK信号SMAD 信号恶性黑色素瘤介质类型的表型表型切换器

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