用局部干燥剂进行化学除菌时的疼痛感知和管理:病例系列分析
Polina Shabes1, Waseem Garabet1, Sven Tilhein2
1Department of Vascular and Endovascular Surgery, University Hospital of Duesseldorf (UKD), Heinrich-Heine University Duesseldorf (HHU), Duesseldorf, Germany.
Journal of wound care
|September 4, 2025
概括
在局部干燥剂 (TDA) 应用时的疼痛可以通过局部麻醉有效地管理. 这种化学除方法显示的疼痛程度与传统的尖除相比相当,甚至更低.
科学领域:
- 伤口护理和管理
- 皮肤病学
- 药理学
背景情况:
- 局部干燥剂 (TDA) 是甲基硫酸 (MSA) 和二甲基硫化物 (DMSO) 的组合,是去除伤口护理中的生物膜和瘤的有效选择.
- 在某些患者中,TDA的使用可能会引起暂时的尖疼痛,因此需要采取疼痛控制策略.
研究的目的:
- 评估与TDA应用相关的疼痛.
- 评估两种局部麻醉策略在治疗TDA相关疼痛方面的有效性.
主要方法:
- 一个回顾性病例系列研究,涉及20名TDA治疗的患者.
- 在TDA应用之前,期间和之后使用视觉模拟量表 (VAS) 评估疼痛.
- 使用了两种疼痛管理策略:麻醉膏和瘤局部麻醉 (TLA).
主要成果:
- 在应用过程中,使用TDA进行化学清除与可变的疼痛水平相关 (VAS 0-10).
- 有效的疼痛管理显著减少了不适,与急性脱皮相比,疼痛评级没有显著差异.
- 在适当的麻醉管理下,患者的疼痛水平与TDA相似或更低.
结论:
- 在TDA化学清除过程中出现的疼痛可以通过随时可用的麻醉方法有效地管理.
- 与急性除相比,当TDA治疗与局部麻醉进行时,不会增加整体疼痛感知.
- 这项研究支持TDA作为一种可行的,耐受性良好的除菌选择,并有效控制疼痛.
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