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研究领域生物医学和临床科学瘤学和致癌症预测和预后标志物
在手术治疗的非小细胞肺癌中复发模式的分类 - - 系统性审查和要求标准化

在手术治疗的非小细胞肺癌中复发模式的分类 - - 系统性审查和要求标准化

Alessandro Bonis ¹, Frank Detterbeck ², Paula Ugalde Figueroa ³, Haiquan Chen ⁴, Raymond Osarogiagbon ⁵, Andrea Dell'Amore ¹, Maurizio Infante ⁶

Alessandro Bonis ¹, Frank Detterbeck ², Paula Ugalde Figueroa ³

¹Thoracic Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Italy.
²Department of Surgery, Yale University School of Medicine, New Haven, CT, USA.
³Division of Thoracic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass, USA.
⁴Division of Thoracic Surgery, Institute of Thoracic Oncology, Fudan University Cancer Center, Shanghai, China.
⁵Multidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN, USA.
⁶Division of Thoracic Surgery, University and Hospital Trust, Ospedale Borgo Trento, Verona, Italy.

⁰Thoracic Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Italy.

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology +

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2025年九月4日

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在PubMed上查看摘要

概括

此摘要是机器生成的。

在手术后癌症复发很常见. 非小细胞肺癌 (NSCLC) 瘤复发模式的定义缺乏一致性,阻碍了研究和患者护理.

科学领域

癌症学
外科瘤学
癌症研究

背景情况

在手术后的癌症复发会在两年内影响30-55%的患者.
瘤复发的分类 (局部,局部区域,远程) 缺乏统一的共识.
标准化定义对于准确解释复发模式至关重要.

研究的目的

系统地审查和分析经过手术治疗的非小细胞肺癌 (NSCLC) 瘤复发的特定位置定义.
评估近期科学文献中的复发模式的一致性和变异性.
强调需要标准化定义以提高研究可比性和临床决策.

主要方法

根据PRISMA指南,对2020年至2024年间发表的研究进行了系统文献审查.
搜索了关于手术治疗的NSCLC的文章,重点是复发定义.
进行描述性分析以评估复发模式分类的一致性.

主要成果

在3082篇选文章中,分析了112篇符合条件的研究.
在手术边缘,支气管和侧节点的复发通常被认为是局部/局部.
在不同叶片,逆侧节,胸壁和胸腔空间的复发中存在变异性.

结论

在手术治疗的NSCLC的复发模式中发现了显著的不一致性.
这种缺乏统一性影响了研究结果和临床结果的可比性.
建立瘤复发的标准定义对于推进癌症研究和改善患者护理至关重要.

关键词:

解剖学位置的定义在 NSCLC 复发模式

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