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在微侵袭性结直肠手术期间预防解剖漏洞的ICG-FA:一个元分析

Muhammad Imran¹, Shahr Yar², Mansab Ali³

¹University College of Medicine and Dentistry, The University of Lahore, Lahore, Pakistan.

The Journal of surgical research

|September 4, 2025

概括

绿色光血管造影 (ICG-FA) 显著降低了微侵袭性结直肠手术中的透和并发症,特别是左侧手术. 然而, 它确实增加了手术时间, 对右侧手术需要进一步的研究.

科学领域:

大肠直肠手术
外科创新
医学成像

背景情况:

在结直肠外科手术后, 解漏是严重的并发症.
绿色光血管学 (ICG-FA) 提供实时输液评估,以潜在地减轻泄漏率.
最近的大型随机临床试验的相互矛盾结果需要进一步调查ICG- FA的疗效.

研究的目的:

评估ICG-FA在减少无管外泄和相关并发症的有效性.
综合随机临床试验的证据,以更清楚地了解ICG-FA的影响.
确定特定的子组,如左侧或右侧解,其中ICG-FA可能提供差异性益处.

主要方法:

在多个数据库中进行了全面的文献搜索.
使用Covidence对相关研究进行了选.
来自6项随机临床试验的数据 (3264名参与者) 通过元分析 (RevMan 5. 4) 综合了风险比率和95%的置信区间.

主要成果:

ICG-FA显著降低了整体道泄漏 (RR: 0.66,P = 0.0005) 和整体并发症 (RR: 0.88,P = 0.03).
观察到左侧解瘤的显著减少 (RR:0. 57,P < 0. 0001),而右侧解瘤的显著减少 (RR:0. 90,P = 0. 68).
在重症并发症 (Clavien- Dindo ≥3),重复手术率或住院时间方面没有发现显著差异;然而,手术时间较长 (MD: 5. 57分钟,P = 0. 006).

结论:

在微侵袭性结直肠手术中,ICG-FA有效地减少了道泄漏和整体并发症,特别是在左侧道.
需要进一步研究ICG-FA对右侧瘤的益处.
虽然ICG-FA增加了手术时间,但它在改善手术结果方面的作用值得考虑,对于长期影响需要进行持续研究.

关键词:

解剖学性泄漏大肠直肠手术光血管学其他国家印度氨酸绿色综合分析最少的侵入性手术

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