结肠囊内镜与常规结肠镜相比:一个随机控制的优越性试验
Camilla Thorndal1, Benedicte Schelde-Olesen2,3, Lasse Kaalby2,3
1Surgical, Odense University Hospital, Odense, Denmark.
大肠囊内镜 (CCE) 是大肠镜的安全和首选替代方案,用于大肠膜炎 (CD) 的后续检查. 患者报告CCE的不适程度较低,表明其作为以患者为中心的诊断工具的潜力.
科学领域:
- 胃肠病学
- 医疗器械
- 临床试验
背景情况:
- 在结肠异炎 (CD) 后进行随访结肠镜检查是标准的,以排除恶性病变.
- 结肠囊内镜 (CCE) 提供了一个不那么侵入性的诊断替代方案.
研究的目的:
- 在CD后的患者中比较CCE与结肠镜.
- 主要关注患者报告的结果,包括不适和检查偏好.
主要方法:
- 在CT验证的CD患者中进行随机对照试验.
- 在出院后4至6周进行的CCE (PillCam Colon 2) 与标准结肠镜的比较.
- 评估患者报告的不适 (VAS分数) 和检查偏好.
主要成果:
- 在CCE和结肠镜检查之间,体验到的身体/精神不适没有显著差异.
- 结肠镜检查的预期不适度得分 (VAS) 较高.
- 大多数患者更喜欢CCE进行未来的检查 (49%对13%).
- 完整检查率:CCE为84%,结肠镜为92%.
- 两组都没有发现恶性瘤.
结论:
- 对于患有结肠膜炎的患者来说,CCE是一种安全的后续程序.
- 大多数患者在未来的检查中更喜欢CCE而不是结肠镜.
- 在这种情况下,CCE显示出作为患者首选的诊断工具的潜力.
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