使用基因组信息对日本黑牛的繁殖特征的同胞抑制
1Graduate school of environmental, life and natural science, Okayama University, Okayama, Japan.
Animal bioscience
|September 4, 2025
概括
日本黑牛的基因组内生育影响生殖特征,比传统方法更高. 基因组评估对于改善牛养殖和保持遗传多样性至关重要.
科学领域:
- 动物遗传学
- 生殖生物学
- 定量遗传学
背景情况:
- 基因组内生育在牲畜群体中越来越令人担忧.
- 了解其对生殖特性的影响对于品种管理至关重要.
- 日本黑牛面临着独特的遗传挑战.
研究的目的:
- 为了评估日本黑牛的基因组杂交.
- 评估基因组内生育对生殖特征的影响,例如第一次分娩年龄 (AFC) 和小牛生产指数 (CPI).
- 确定与内生抑郁相关的基因组区域.
主要方法:
- 对8,553头日本黑牛 (2001年至2005年出生) 的生殖记录和SNP数据进行分析.
- 基因组内生育评估使用782只动物的SNP数据.
- 统计建模以估计AFC和CPI的同胞抑郁影响.
主要成果:
- 基因组内生育水平高于传统的系数.
- 在小牛产量指数 (CPI) 中检测到显著的内生抑制,但不是第一次分娩时的年龄 (AFC).
- 染色体12,15和27与CPI近亲繁殖抑郁症有关;染色体4与AFC有关.
结论:
- 基因组内生殖有效地发现了日本黑牛的生殖能力下降.
- 基因组评估对于优化育种策略至关重要.
- 通过基因组洞察保持遗传多样性是提高生殖表现的关键.
相关概念视频
Incomplete Dominance
25.4K
Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.
25.4K
Heritability
301
Heritability is a statistical concept that measures the degree to which genetic differences among individuals contribute to trait variations within a population. It is a fundamental idea in genetics, often prone to misinterpretation. Heritability is expressed as a percentage, reflecting the proportion of variation in a specific trait across a population that can be linked to genetic differences. However, it's important to understand that heritability does not determine how "genetic"...
301
Trihybrid Crosses
23.7K
Trihybrid Crosses
Some of Mendel’s crosses examined three pairs of contrasting characteristics. Such a cross is called a trihybrid cross. A trihybrid cross is a combination of three individual monohybrid crosses. For example, plant height (tall vs. short), seed shape (round vs. wrinkled), and seed color (yellow vs. green).
The F1 generation plants of a trihybrid cross are heterozygous for all three traits and produce eight gametes. Upon self-fertilization, these gametes have an equal...
Some of Mendel’s crosses examined three pairs of contrasting characteristics. Such a cross is called a trihybrid cross. A trihybrid cross is a combination of three individual monohybrid crosses. For example, plant height (tall vs. short), seed shape (round vs. wrinkled), and seed color (yellow vs. green).
The F1 generation plants of a trihybrid cross are heterozygous for all three traits and produce eight gametes. Upon self-fertilization, these gametes have an equal...
23.7K
Animal Mitochondrial Genetics
8.0K
Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
8.0K
Genomic Imprinting and Inheritance
35.2K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
35.2K
Genetic Variation
387
Genetic variation is the diversity in DNA sequences found among individuals of the same species. This diversity is crucial for a species' survival because it helps organisms adapt to environmental changes. Genetic variation begins with fertilization, where an egg and sperm cell merge. Each of these cells carries 23 chromosomes, up to 46 in the fertilized egg. Chromosomes are long DNA strands that contain genes, the basic units of heredity.
Genes exist in different versions called alleles,...
Genes exist in different versions called alleles,...
387


