相关实验视频

Updated: Jun 10, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
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RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma

Published on: March 11, 2014

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在 Vulvar 状细胞癌 (VSCC) 中的 Nectin4 表达的评估:与 HPV 相关和 HPV 独立的分子亚型的相关性

Anne Kathrin Höhn1, Grit Gesine Ruth Hiller1, Benjamin Wolf2

  • 1Division of Gynecologic, Breast and Perinatal Pathology, Institute of Pathology, University Hospital Leipzig, Germany.

Human pathology
|September 4, 2025
PubMed
概括

大多数状细胞癌 (VSCC) 都表达Nectin4,这是抗体与药物联合体 (ADC) 的标. 这表明Enfortumab- Vedotin (EV) 可能是对VSCC的潜在治疗方法,需要进一步进行临床试验.

关键词:
尼克4抗体与药物的结合物分子状细胞癌分类型针对性的治疗阴道

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Four-color Fluorescence Immunohistochemistry of T-cell Subpopulations in Archival Formalin-fixed, Paraffin-embedded Human Oropharyngeal Squamous Cell Carcinoma Samples07:43

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Chromogenic In Situ Hybridization as a Tool for HPV-Related Head and Neck Cancer Diagnosis06:57

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Cancer-Critical Genes II: Tumor Suppressor Genes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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