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对瘤学预测模型研究的同行评审需要改进:对BMC期刊公开的同行评审报告进行系统审查
Jie Ma1, Angela MacCarthy1, Shona Kirtley1
1Centre for Statistics in Medicine, UK EQUATOR Centre, Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences, University of Oxford, Oxford United Kingdom.
Journal of clinical epidemiology
|September 4, 2025
概括
对瘤临床预测模型的同行评价是简短的,缺乏深度,未能执行报告准则或严格评估方法. 这种监督可能会对患者造成伤害,
科学领域:
- 癌症学
- 生物统计学
- 医疗信息学
背景情况:
- 临床预测模型 (CPM) 在瘤学中对患者护理至关重要.
- 开放的同行评审 (OPR) 旨在提高科学手稿的质量.
- 对CPM等复杂模型进行OPR质量的评估是必不可少的.
研究的目的:
- 在BMC期刊中评估瘤CPM的OPR报告的完整性和质量.
- 检查是否遵守方法标准和报告准则 (例如,TRIPOD).
- 评估OPR报告中提供的反的建设性.
主要方法:
- 在2021年发表的瘤CPM研究中搜索了BMC期刊.
- 使用ARCADIA检查清单和额外的数据提取标准.
- 两个独立的调查人员评估了OPR报告,第三方解决冲突.
主要成果:
- OPR报告简洁 (中位数为243字),很少涉及局限性或通用性.
- 没有审查人员验证了遵守TRIPOD等报告准则.
- 审查优先考虑表面因素 (67.3%) 而不是方法严格性 (38.5%的统计方法).
结论:
- 对瘤CPM的OPR缺乏深度,方法审查和报告标准的执行.
- 这种缺陷可能会造成偏见模型和研究浪费的临床损害.
- 紧急改革包括实施指导方针 (TRIPOD+AI),审查员培训,并将同行评审视为学术工作.
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