在接受固体瘤切除的儿科瘤患者中出现早期的术后发烧
John Lundstedt1, Emily Vore1, Joseph Brungardt1
1Division of Pediatric General and Thoracic Surgery. Cincinnati Children's Hospital Medical Center. 3333 Burnet Avenue, Cincinnati, Ohio 45229.
Journal of pediatric surgery
|September 4, 2025
概括
术后发烧在儿童癌症患者中很常见, 但真正的感染很少见. 避免在前两天进行昂贵的发烧检查和广泛的检测,除非出现明显的症状.
科学领域:
- 儿童瘤学
- 传染性疾病
- 临床研究
背景情况:
- 在切除癌症后,儿科瘤患者经常出现术后发烧.
- 这往往导致广泛而昂贵的诊断工作.
- 确定真正的感染发病率和风险因素至关重要.
研究的目的:
- 在瘤患者中确定术后发烧的发生率.
- 确定与手术后发烧相关的危险因素.
- 评估真实感染的发生率和发烧检查的有用性.
主要方法:
- 从2018年至2023年对儿科瘤患者的回顾性图表.
- 分析变量包括化疗,中枢线,手术类型,输血和中性质减退.
- 用于分析发烧预测的通用线性混合模型.
主要成果:
- 在222名患者中,有42%的患者出现了早期的术后发烧.
- 预测因素包括输血,福利导管,中性质减退和肉瘤组织学.
- 只有2. 8%的发烧患者有可治疗的感染病因.
结论:
- 在儿童癌症患者中,术后发烧是常见的,但很少表明感染.
- 实验性抗生素治疗和广泛的检查往往是不必要的.
- 只有有显著症状的患者应接受发烧检查.
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