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与癌症相关的认知障碍的运动干预:一个总体审查
Chen Hu1, Yanfang Zheng, Shuyan Xing2
1Shanxi Medical University School of Nursing, Taiyuan, 030001, Shanxi, China.
American journal of physical medicine & rehabilitation
|September 4, 2025
概括
运动干预有效管理与癌症相关的认知障碍 (CRCI). 有氧运动显著改善客观认知功能, 而心身运动减轻了癌症幸存者的主观抱怨.
科学领域:
- 癌症学
- 神经科学
- 运动科学
背景情况:
- 与癌症相关的认知障碍 (CRCI) 是影响癌症幸存者的普遍和削弱性疾病.
- 现有的非药物治疗CRCI需要强有力的证据来指导临床实践.
- 运动是缓解癌症患者认知缺陷的一个有希望的途径.
研究的目的:
- 进行总体审查,评估运动干预措施在癌症幸存者中预防和管理CRCI的有效性.
- 提供基于证据的基础,将运动纳入CRCI的临床治疗策略.
- 综合不同运动方式及其对认知功能的现有证据.
主要方法:
- 对癌症患者的认知改善进行了预先注册的系统性审查.
- 使用AMSTAR 2来评估所包含的系统审查的质量和综合证据的一致性.
- 包括28项系统审查,考察各种运动类型,包括有氧运动,心身运动和综合训练.
主要成果:
- 高质量的证据支持有氧运动可显著改善客观认知能力 (例如,HVLT,TMT-A).
- 心身运动在减少主观认知投诉方面表现出显著的有效性 (例如,FACT-Cog).
- 综合训练对整体认知功能的初步协同作用;抵抗训练的证据有限.
结论:
- 运动干预是治疗CRCI的重要非药物策略.
- 未来的研究应优先考虑高质量的RCT,多模式评估框架和个性化的练习指南.
- 澄清运动引起的认知改善的生物学机制对于精确的运动处方至关重要.
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