透气导管大动脉置换后的体质指数和结果:来自跨太平洋TAVR注册的见解
Eric P Cantey1, Ashraf Samhan2, Abigail S Baldridge2
1Division of Cardiology, Department of Medicine, University of Michigan, Ann Arbor, Michigan, USA.
JACC. Asia
|September 4, 2025
概括
甲状腺置换前导管 (TAVR) 的体重指数 (BMI) 没有影响患者的整体存活率. 然而,体重不足的患者在TAVR后表现出更好的左心室重塑和血液动力学.
科学领域:
- 心脏病学
- 医学研究
- 临床结果
背景情况:
- 在
- 肥胖悖论
- 在透过导管的大动脉置换 (TAVR) 后,这表明肥胖患者的治疗结果有所改善.
研究的目的:
- 研究TAVR前的体重指数 (BMI) 和TAVR后的体重指数变化对临床和心声学结果的影响.
主要方法:
- 对1339名接受TAVR (2015-2019) 的严重大动脉狭窄患者的分析.
- 根据BMI分层的患者 (体重不足,正常,超重,肥胖).
- 主要结局:整体存活;次要结局:存活,出血,血管损伤,中风,急性损伤.
主要成果:
- 在1. 1年的中位随访期内,BMI组之间的整体存活率没有显著差异.
- 体重较低的患者年龄较大,患慢性病和主动脉吐率较高.
- 肥胖患者有更多的动脉样硬化心血管疾病风险因素.
- 在1年的随访期内,体重不足的患者表现出左心室重塑和血液动力学方面的改善.
结论:
- 在TAVR前的BMI没有显著影响临床结果,挑战了肥胖悖论.
- 在TAVR后,体重不足的患者在左心室重塑和膜血液动力学方面表现出微妙的改善.
- BMI 在 TAVR 恢复和结果中起着微妙的作用.
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