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蚊子中的微生物用于控制蚊子传播的病毒性疾病:从实验室到现场

Jianying Liu¹, Liming Zhang², Hua Tong³

¹New Cornerstone Science Laboratory, Tsinghua University-Peking University Joint Center for Life Sciences, School of Basic Medical Sciences, Tsinghua University, Beijing 100084, China; Institute of Infectious Diseases, Shenzhen Bay Laboratory, Shenzhen 518000, China; Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Shenzhen 518060, China; Institute of Virology, Shiyan Key Virology Laboratory, School of Basic Medical Sciences, Hubei University of Medicine, Shiyan 442000, China.

Trends in microbiology

|September 4, 2025

概括

微生物剂为蚊子控制提供了可持续的替代方案,解决了杀虫剂耐药性和生态问题. 这篇评论强调了基于微生物的策略对抗蚊子传播的病毒性疾病的进展.

科学领域:

* 媒介性疾病控制
* 微生物害虫防治
* 可持续的昆虫学

背景情况:

蚊子传播的病毒性疾病是全球重大且不断升级的健康挑战.
* 疫苗和抗病毒药物的有限可用性需要有效的病媒控制方法.
传统的杀虫剂使用受到广泛的耐药性和环境问题所阻碍.

研究的目的:

* 审查基于微生物的蚊子控制策略的进展.
* 评估微生物剂的机制,转化相关性和现场适用性.
* 确定有前途的微生物候选人用于未来的载体控制计划.

主要方法:

* 针对蚊子的微生物防治剂的综合文献审查.
* 专注于已证明在现场成功的细菌,真菌和病毒病原体.
* 作用机制和生态影响的分析.

主要成果:

* 微生物,包括细菌和真菌,显示出抑制蚊子数量的巨大潜力.
* 几种微生物候选物已经从实验室研究发展到现场实践.
* 多种作用机制有助于微生物控制的有效性.

结论:

微生物衍生剂是传统杀虫剂的可行,可持续的替代品.
进一步的研究和战略整合对于下一代载体控制工具至关重要.
* 开发微生物策略是管理蚊子传播病毒疾病威胁的关键.

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