氧化平衡得分与妊娠糖尿病风险之间的关联:一个病例对照研究
Fatemeh Maleki Sedgi1, Amir Hossein Hassani1, Amir Hossein Faghfouri1
1Maternal and Childhood Obesity Research Center, Urmia University of Medical Sciences, Urmia, Iran.
BMC endocrine disorders
|September 4, 2025
概括
较高的氧化平衡评分 (OBS),反映了富含抗氧化剂的饮食和健康的生活方式选择,与妊娠糖尿病 (GDM) 的风险较低有关. 这表明OBS是GDM预防策略的宝贵工具.
科学领域:
- 营养科学
- 母亲健康
- 氧化应激研究
背景情况:
- 孕期糖尿病 (GDM) 是一个常见的妊娠并发症.
- GDM与氧化应激的增加密切相关.
- 氧化平衡评分 (OBS) 量化了影响氧化压力的饮食和生活方式因素.
研究的目的:
- 研究氧化平衡评分 (OBS) 与妊娠糖尿病 (GDM) 风险之间的关联.
- 探索OBS和GDM风险的饮食和生活方式组成部分之间的关系.
主要方法:
- 一个涉及150名患有GDM的孕妇和170名健康对照者的病例对照研究.
- 通过168项食物频率问卷 (FFQ) 评估饮食摄入量.
- 从饮食和生活方式的亲氧化和抗氧化因素计算OBS;用于分析的后勤回归.
主要成果:
- 与对照组相比,患有GDM的女性的总体和饮食OBS显著降低.
- 在GDM组中观察到关键抗氧化剂 (利黄素,叶酸,,) 的摄入量较低.
- 较高的OBS三位数与GDM风险降低23%有关;较高的饮食和生活方式OBS与GDM呈反向关联.
结论:
- 较高的氧化平衡得分,包括饮食和生活方式因素,与妊娠糖尿病风险相反相关.
- 这些发现强调了富含抗氧化剂的饮食和健康的生活方式在预防GDM方面的潜在作用.
- OBS可以作为评估GDM风险和指导预防干预的有价值指标.
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