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Updated: Sep 9, 2025

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在小鼠中急性循环失调的转录和代谢特征

Baoyin Ren1,2,3, Yingzhi Huang2, Hui Wang4

  • 1WuHu Hospital, East China Normal University (The Second People's Hospital, Wuhu), Wuhu, China.

Journal of pineal research
|September 5, 2025
PubMed
概括

即使行为节奏从时差中恢复过来, 分子痕迹仍然存在. 这项研究确定了特定的基因和代谢物变化,以及l-Serine作为昼夜失调的潜在生物标志物.

关键词:
Bmal1 没有生物标志物昼夜调整失调代谢学转录组学

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The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
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