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Updated: May 5, 2026

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一个临床前研究:OdanaCatib涂层支持植入物的骨质整合

Natália Dos Santos Sanches1,2, Caroline Liberato Marchiolli1, Lara Cristina Cunha Cervantes1,3

  • 1Department of Diagnosis and Surgery, São Paulo State University (UNESP), School of Dentistry Araçatuba, São Paulo, Brazil.

Clinical oral implants research
|September 5, 2025
PubMed
概括

在大鼠中,局部用Odanacatib (ODN) 是一种甲素K抑制剂,可提升牙植入物的早期骨质整合. 这种药物有助于骨愈合和植入物稳定,

关键词:
生物机械测试牙科植入物组织形态测量其他药物骨质整合一个老鼠在微型电路上

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Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
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