释放营养药在癌症化疗中的潜力:全面审查
Pravesh Aggarwal1, Gitashree Dutta2, Rekha Shaurya3
1Pharmacology, All India Institute of Medical Sciences, Jodhpur, Jodhpur, IND.
Cureus
|September 5, 2025
概括
营养药可以作为癌症治疗的辅助剂, 增强化疗和减少副作用. 然而,不一致的试验和安全问题需要仔细,基于证据的整合到瘤治疗中.
科学领域:
- 癌症学
- 营养科学
- 药理学
背景情况:
- 癌症是全球主要的健康挑战.
- 传统的癌症治疗包括化疗和放射治疗.
- 营养药,天然化合物, 显示作为补充癌症治疗的潜力.
研究的目的:
- 审查癌症化疗中营养药的机制和治疗作用.
- 确定与营养药在瘤学中的使用相关的临床挑战.
- 综合有关癌症患者辅助营养药物干预的现有证据.
主要方法:
- 从2015年到2024年的文献叙事审查.
- 在PubMed,Scopus和Web of Science进行的搜索.
- 根据癌症,营养药和结果的相关性选择的研究.
主要成果:
- 营养药物 (例如黄素,白醇,维生素) 具有抗氧化,抗炎和促死作用.
- 许多营养药与化疗有协同作用,提高疗效,降低毒性.
- 益生菌和omega-3脂肪酸可以减轻化疗的副作用.
结论:
- 营养药在癌症治疗中具有潜在的辅助益处.
- 临床应用受到不一致的结果,剂量问题和生物可用性的阻碍.
- 标准化,严格的试验和监管对于安全有效的使用至关重要.
更多相关视频
15:04Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation
Published on: January 19, 2019
12.3K
09:19Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo
Published on: February 6, 2015
8.8K
相关概念视频
02:50Combination Therapies and Personalized Medicine
5.1K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
5.1K
02:57Targeted Cancer Therapies
7.8K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.8K
02:49Cancer Therapies
7.9K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.9K
01:30Cancer Vaccines
509
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
509
01:27Tumor Immunotherapy
658
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
658
02:59Cancer Prevention
6.3K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.3K