在获取和分析技术之间,左心室全球纵向应变的可靠性:前性比较研究
FeiFei Gong1, Nausheen Akhter1, Inga Vaitenas1
1Bluhm Cardiovascular Institute, Northwestern University, Chicago, IL 60601, USA.
European heart journal. Imaging methods and practice
|September 5, 2025
概括
左心室全球纵向应变 (GLS) 在2D和3D回声心脏学方法中可重现. 然而,3D GLS低于2D GLS,不应互换使用.
科学领域:
- 心血管成像
- 心声检查
- 心脏机械学
背景情况:
- 左心室全球纵向应变 (GLS) 是亚临床缩功能障碍的敏感指标.
- 声心图采集和分析的变化可能会影响GLS测量的临床效用.
- 为了确保可靠的GLS评估,需要进行标准化.
研究的目的:
- 使用不同的二维和三维回声心脏成像方法来评估LV GLS的准确性,可变性和相关性.
- 为了比较来自特定供应商和供应商中立软件平台的GLS测量.
- 评估二维和三维GLS测量的可互换性.
主要方法:
- 对254名连续接受心声扫描的患者进行前性分析.
- 使用多种2D (三拍,单拍) 和3D采集方法进行GLS测量.
- 使用EchoPac和TomTec-Arena软件进行的分析;统计分析包括皮尔森相关性,ICC和Bland-Altman分析.
主要成果:
- 在获取方法和软件平台之间,GLS值的高度一致性.
- 2D GLS的观察者内部和观察者间变异性较低 (ICC>0.9),表明其可重现性很好.
- 3D GLS值明显低于2D GLS值 (平均差异为- 4. 3%),相关性中等 (r=0. 66),表明它们是不可互换的.
结论:
- LV GLS是评估LV功能的可靠方法,具有很强的可重复性.
- 3D GLS测量总是低于2D GLS,不应互换使用.
- 在2D和3D方法中比较GLS值时,需要进行持续的标准化和谨慎.
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