病例报告:长期口服 stanozolol 导致的肝细胞腺瘤
Ya-Nan Qin1, Chang-Ming Tao1, Tian-Tian Guo2
1Department of Infectious Diseases, Liaocheng People's Hospital, Liaocheng, China.
Frontiers in medicine
|September 5, 2025
概括
长期使用 stanozolol 治疗无质性贫血可能会增加肝脏瘤的风险. 停用 stanozolol 和支持性治疗导致肝细胞腺瘤大小的减少.
科学领域:
- 肝病学
- 血液学
- 癌症学
背景情况:
- 无细胞性贫血是一种罕见的骨髓衰竭疾病.
- 长期治疗无塑性贫血通常需要药物来刺激血细胞的产生.
- 肝细胞腺瘤是一种罕见的良性肝瘤.
研究的目的:
- 报告一个罕见的肝细胞腺瘤病例.
- 调查 stanozolol 治疗与肝细胞腺瘤发展之间的潜在联系.
- 强调长期服药患者的警监测的重要性.
主要方法:
- 一个15岁的男性患有无细胞性贫血.
- 对口服 stanozolol 的长期治疗和肝功能监测的审查.
- 肝细胞腺瘤的诊断通过肝脏活检得到确认.
- 通过导管进行肝动脉栓塞的干预和停止使用 stanozolol.
- 随访成像,以评估治疗反应.
主要成果:
- 在接受长期 stanozolol 治疗的患者中发现了一种肝瘤,被诊断为β-catenin 激活的肝细胞腺瘤.
- 斯坦诺佐洛尔被取消并被替换为罗米普洛斯蒂姆.
- 由于出血风险,进行了肝动脉栓塞.
- 随访CT扫描显示,在停止使用 stanozolol 后,瘤大小显著减少.
结论:
- 长期的雄激素治疗,如 stanozolol,可能会在无形成性贫血患者中产生肝细胞腺瘤的风险.
- 这一案例强调了对这种患者群体的最佳管理和监测策略的需要.
- 在长期接受 stanozolol 治疗的无形成性贫血患者中,可能需要定期进行腹部成像.
相关概念视频
Chronic Pancreatitis I: Introduction
147
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
147
Diseases of the Liver and Gallbladder
957
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
957


