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Updated: Sep 9, 2025

In Vitro Assays to Assess Blood-brain Barrier Mesh-like Vessel Formation and Disruption
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血管蛋白信号是阿尔茨海默病中粉样蛋白驱动的血管功能障碍的中心轴

Matthias Flotho, Andrew Yang, Fabian Kern

    bioRxiv : the preprint server for biology
    |September 5, 2025
    PubMed
    概括

    阿尔茨海默病 (AD) 血管功能障碍源于基因表达的变化,而不是细胞数量的变化,在轻微的认知障碍早期影响大脑内皮细胞和光滑肌肉细胞. 血管蛋白信号失调是阿尔茨海默病进展的关键因素.

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