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Updated: Sep 9, 2025

Analysis of SCAP N-glycosylation and Trafficking in Human Cells
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Analysis of SCAP N-glycosylation and Trafficking in Human Cells

Published on: November 8, 2016

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通过针对性招募SCF-FBXO22进行NSD2降解的结构基础

Kevin C Robertson, Sascha J Amann, Tongkun Liu

    bioRxiv : the preprint server for biology
    |September 5, 2025
    PubMed
    概括

    研究人员使用新型化学探针发现FBXO22蛋白如何与NSD2结合, 这一发现推动了针对癌症治疗的向蛋白降解 (TPD) 策略.

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    Using In Vitro Fluorescence Resonance Energy Transfer to Study the Dynamics Of Protein Complexes at a Millisecond Time Scale10:50

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