作为年龄,种族和社会经济地位的函数,研究情绪调节的神经相关性
bioRxiv : the preprint server for biology
|September 5, 2025
概括
年长的成年人表现出更好的情绪调节, 随着年龄的增长,
科学领域:
- 神经科学
- 老年学
- 社会学
背景情况:
- 老龄化通常与情绪调节的改善有关,
- 这种改善与前额叶皮质对杏仁核反应的增强控制有关.
- 由于种族歧视和社会经济劣势造成的慢性压力可能会破坏与年龄有关的典型神经变化.
研究的目的:
- 研究不同种族和社会经济地位 (SES) 群体在情绪调节中的年龄相关神经关联.
- 特别研究杏仁体激活和vmPFC-杏仁体连接性.
- 了解边缘化对大脑健康和情绪调节的影响.
主要方法:
- 从50-78岁的8,711名英国生物库参与者中使用任务功能性MRI数据.
- 分析了桃体激活和vmPFC-桃体功能连接的年龄相关变化.
- 在不同种族和SES群体中比较这些神经关联.
主要成果:
- 年龄较大与杏仁体活化降低相关,表明情绪调节改善.
- 较低的SES与桃体活化增加有关,这表明压力反应性增加.
- 没有发现人群年龄对vmPFC-杏仁核连接性的影响;黑人参与者表现出与年龄相关的连接性下降.
结论:
- 虽然老龄化通常会改善情绪调节, 但长期的压力会改变这些神经模式.
- 社会经济地位对老年人与压力相关的大脑反应有重大影响.
- 神经成像研究需要更多的多样性,
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