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Updated: Sep 9, 2025

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

Published on: August 16, 2018

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作为第一个双功能TREM2调节器:受体激活和除抑制

Sungwoo Cho, Farida El Gaamouch, Saurabh Upadhyay

    bioRxiv : the preprint server for biology
    |September 5, 2025
    PubMed
    概括

    一种名为As48的新药激活TREM2信号并阻止其脱落,通过增强微质功能和大脑修复机制,为阿尔茨海默病提供一种新的治疗策略.

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