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Updated: Sep 9, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

Published on: March 15, 2024

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在代谢功能障碍相关的脂肪酸性肝病中,肝脏的铁素还原酶调节线粒体功能和铁稳态

Tomoaki Tanaka, Ikki Sakuma, Rafael Gaspar

    Research square
    |September 5, 2025
    PubMed
    概括

    费雷多克辛减少酶 (FDXR) 缺乏会通过损害线粒体功能和增加铁量而使代谢功能失调相关的脂肪性肝病 (MASLD) 恶化. 在MASLD中升级的FDXR表明具有保护作用,其恢复可以改善肝脏肥胖症.

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