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罕见的无痛血性初级恶性黑色素瘤:一个病例报告
Yuchun Zhong1,2, Yueji Zou3, Long Peng1
1Department of General Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Frontiers in oncology
|September 5, 2025
概括
直肠恶性黑色素瘤 (ARMM) 是罕见的,并且经常被误诊. 准确的诊断依赖于组织病理学和免疫组织化学,指导通过手术和免疫治疗获得更好的结果的多学科治疗.
科学领域:
- 胃肠病学
- 癌症学
- 病理学
背景情况:
- 阳门恶性黑色素瘤 (ARMM) 是一种罕见的侵袭性癌症.
- 这种疾病的患病率很低,诊断错误率很高,并且经常复发.
- 临床表现可能模仿直肠癌.
研究的目的:
- 报告一个ARMM病例.
- 突出诊断挑战和免疫组织化学 (IHC) 的作用.
- 为了说明不断发展的多学科治疗方法.
主要方法:
- 一位51岁的女性患有直肠出血的症状.
- 诊断工作包括数字直肠检查,结肠镜,组织病理学和IHC (MelanA,S100,Ki-67).
- 治疗包括腹腔镜辅助腹膜切除和辅助托利帕利马布免疫治疗.
主要成果:
- 最初的怀疑是直肠癌, 但IHC证实ARMM.
- 患者接受了成功的手术切除和辅助治疗.
- 在3个月的随访期内没有发现复发.
结论:
- 在临床上,ARMM与直肠癌无法区分,因此需要IHC进行准确的诊断.
- 整合手术和免疫治疗的多学科治疗有希望.
- 通过IHC进行准确的诊断对于ARMM的有效管理至关重要.
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