拉脱维亚的慢性血栓栓塞性肺高血压:从2024年开始的流行病学见解和诊断挑战
Matiss Zicans1, Kristaps Sablinskis1, Haralds Cesnieks2
1Riga Stradins University Riga Latvia.
Pulmonary circulation
|September 5, 2025
概括
在拉脱维亚,在2024年诊断出15例慢性血栓塞性肺高血压 (CTEPH),显示出严重的发病率. 早期诊断至关重要,因为延迟检测与CTEPH患者的肺血管阻力更高有关.
科学领域:
- 心脏病学
- 肺病学
- 流行病学
背景情况:
- 慢性血栓塞性肺高血压 (CTEPH) 是由未解决的肺动脉阻塞引起的严重疾病.
- 未被诊断的CTEPH病例导致严重的临床负担,患病率各不相同.
- 准确的流行病学数据和了解诊断途径对于改善CTEPH管理至关重要.
研究的目的:
- 总结2024年拉脱维亚诊断的所有CTEPH病例.
- 计算拉脱维亚每年的CTEPH发病率和流行率.
- 确定CTEPH患者的风险因素并分析诊断时间表.
主要方法:
- 一项观察性研究分析了拉脱维亚在2024年诊断的所有CTEPH病例.
- 在保罗斯特拉丁斯临床大学医院确认诊断,遵守ESC指南.
- 通过EMPHasis-10问卷和结构化患者访谈收集数据.
主要成果:
- 拉脱维亚在2024年诊断出15例CTEPH病例,每百万人口中有8.01例.
- 患病率为每百万人中的31.51,死亡率为每100人/年中的3.74.
- 以前的急性肺栓塞是最常见的风险因素 (80%);60%的诊断延迟了两年.
结论:
- 由于CTEPH的诊断和治疗往往是错误的,因此需要更好地识别风险因素.
- 拉脱维亚的延迟诊断与延迟转诊到专门的肺高血压中心有关.
- 加强合作和早期识别CTEPH对于优化患者结果至关重要.
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