基于早晚偏好的癌症患者日间节律评估:一个横截面研究
Ghazal Daftari1, Mahsa Abbaszadeh2, Sahar Karimpour Reyhan2
1Department of Internal Medicine Imam Khomeini Hospital Complex Tehran University of Medical Sciences Tehran Iran.
Health science reports
|September 5, 2025
概括
癌症患者表现出正常的昼夜节律. 这项研究研究了150名癌症患者的昼夜节律,发现昼夜节律类型的正常分布,这表明这一群体的节律规律.
科学领域:
- 时间生物学
- 癌症学
- 睡眠医学
背景情况:
- 昼夜节律影响关键的生理功能,包括睡眠和清醒周期,细胞过程和癌症的发展.
- 了解癌症患者的昼夜节律模式对于潜在的治疗干预至关重要.
研究的目的:
- 在癌症患者群体中调查和描述昼夜节律模式.
- 评估这一患者群体中昼夜节律类型的分布.
主要方法:
- 一项涉及150名入院癌症患者的横截面研究.
- 数据收集包括人口特征和早上晚上问卷 (MEQ).
- 统计分析采用差异分析 (ANOVA) 和费舍尔精确测试来比较昼夜节律类型.
主要成果:
- 参与者的平均年龄为49. 83 ± 14. 53岁.
- 非血液性癌症占比 (82. 7%),乳腺癌是最常见的 (23. 3%).
- 平均MEQ分数为56. 6±6. 34,表明昼夜节律模式的正常分布.
结论:
- 研究结果表明,昼夜节律在癌症患者队列中正常分布.
- 这些结果提供了癌症患者昼夜节律模式的基线数据.
相关概念视频
01:15Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response
123
Circadian rhythms are cyclic changes that are crucial in plasma drug concentrations. Various standard circadian parameters, including core body temperature, heart rate, and other cardiovascular factors, directly impact disease states and the therapeutic response to drug therapy.
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
123
02:19Circadian Rhythms and Gene Regulation
4.1K
The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
4.1K
02:45Biological Clocks and Seasonal Responses
37.9K
The circadian—or biological—clock is an intrinsic, timekeeping, molecular mechanism that allows plants to coordinate physiological activities over 24-hour cycles called circadian rhythms. Photoperiodism is a collective term for the biological responses of plants to variations in the relative lengths of dark and light periods. The period of light-exposure is called the photoperiod.
37.9K
01:21Cancer Survival Analysis
445
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
445
01:29Assessment of the Gastrointestinal System II: Health Perception Pattern
162
Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
162