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Updated: Sep 9, 2025

Routine Collection of High-Resolution cryo-EM Datasets Using 200 KV Transmission Electron Microscope
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Routine Collection of High-Resolution cryo-EM Datasets Using 200 KV Transmission Electron Microscope

Published on: March 16, 2022

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麦哲伦 - - 一个可扩展的冷电磁数据可视化,管理和处理平台

Behdad Khoshbin1, Puneeth Damodar1, Rupali R Garje2

  • 1Institute of Molecular Biophysics, Florida State University, Tallahassee, FL, USA.

IUCrJ
|September 5, 2025
PubMed
概括

麦哲伦是一个新的单粒子冷电子显微镜 (cryo-EM) 软件平台,可简化数据处理和分析. 它的微服务架构为研究宏分子结构的研究人员提供了灵活性和可扩展性.

关键词:
马格伦岛自动化化电磁场数据处理大分子结构结构生物学

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相关概念视频

Cryo-electron Microscopy01:28

Cryo-electron Microscopy

Conventional electron microscopy (EM) involves dehydration, fixation, and staining of biological samples, which distorts the native state of biological molecules and results in several artifacts. Also, the high-energy electron beam damages the sample and makes it difficult to obtain high-resolution images. These issues can be addressed using cryo-EM, which uses frozen samples and gentler electron beams. The technique was developed by Jacques Dubochet, Joachim Frank, and Richard Henderson, for...
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