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相关概念视频

The Electron Transport Chain01:30

The Electron Transport Chain

17.3K
The electron transport chain or oxidative phosphorylation is an exothermic process in which free energy released during electron transfer reactions is coupled to ATP synthesis. This process is a significant source of energy in aerobic cells, and therefore inhibitors of the electron transport chain can be detrimental to the cell's metabolic processes.
Inhibitors of the electron transport chain
Rotenone, a widely used pesticide, prevents electron transfer from Fe-S cluster to ubiquinone or Q...
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Electron Transport Chain Components01:29

Electron Transport Chain Components

203
The electron transport chain (ETC) is a crucial metabolic pathway that facilitates energy conversion in prokaryotic and eukaryotic cells. In eukaryotes, the ETC comprises four membrane-associated protein complexes in the inner mitochondrial membrane. In prokaryotes, the ETC in the plasma membrane can vary in composition, with fewer or different complexes depending on the organism and environmental conditions. These complexes transfer electrons from electron donors, such as NADH and FADH2, to...
203
Chemiosmosis and ATP Synthesis01:22

Chemiosmosis and ATP Synthesis

196
The electron transport chain is a critical component of cellular respiration, occurring in the inner mitochondrial membrane. It facilitates the transfer of high-energy electrons from reduced cofactors NADH and FADH₂ to molecular oxygen, the final electron acceptor. This transfer of electrons through a series of protein complexes is tightly coupled to the translocation of protons across the membrane, generating a proton gradient essential for ATP synthesis.Electron Flow and Proton...
196
Electron Transport Chain: Complex III and IV01:43

Electron Transport Chain: Complex III and IV

8.0K
During the electron transport chain, electrons from NADH and FADH2 are first transferred to complexes I and II, respectively. These two complexes then transfer the electrons to ubiquinol, which carries them further to complex III. Complex III passes the electrons across the intermembrane space to Cyt c, which carries them further to complex IV. Complex IV donates electrons to oxygen and reduces it to water. As electrons pass through complexes I, III, and IV, the energy released aids the pumping...
8.0K
Electron Transport Chains01:28

Electron Transport Chains

102.4K
The final stage of cellular respiration is oxidative phosphorylation that consists of two steps: the electron transport chain and chemiosmosis. The electron transport chain is a set of proteins found in the inner mitochondrial membrane in eukaryotic cells. Its primary function is to establish a proton gradient that can be used during chemiosmosis to produce ATP and generate electron carriers, such as NAD+ and FAD, that are used in glycolysis and the citric acid cycle.
The ETC is comprised of...
102.4K
ATP Driven Pumps I: An Overview01:27

ATP Driven Pumps I: An Overview

8.5K
ATP-driven pumps, also known as transport ATPases, are integral membrane proteins. They have binding sites for ATP located on the membrane's cytosolic side and the ion-conducting domain in the transmembrane region. These pumps use the free energy released from ATP hydrolysis to move the solutes across cell membranes against an electrochemical gradient.
There are four main types of ATP-driven pumps - P-type, V-type, F-type, and ABC transporter. All these pumps are of varying complexities and...
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相关实验视频

Updated: Sep 9, 2025

Electrochemical Impedance Spectroscopy as a Tool for Electrochemical Rate Constant Estimation
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Electrochemical Impedance Spectroscopy as a Tool for Electrochemical Rate Constant Estimation

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关于计算非adiabatic质子合电子转移速率常数的教程

Phillips Hutchison1, Kai Cui2, Jiayun Zhong2

  • 1Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, New Jersey 08544, USA.

The Journal of chemical physics
|September 5, 2025
PubMed
概括
此摘要是机器生成的。

质子合电子转移 (PCET) 是跨科学领域的基础. 本教程详细介绍了PCET速率常数的计算,包括像质子道化这样的量子效应,使用pyPCET套件用于各种系统.

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Proton Transfer and Protein Conformation Dynamics in Photosensitive Proteins by Time-resolved Step-scan Fourier-transform Infrared Spectroscopy
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Last Updated: Sep 9, 2025

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A Micro-agar Salt Bridge Electrode for Analyzing the Proton Turnover Rate of Recombinant Membrane Proteins
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科学领域:

  • 多学科科学
  • 物理化学
  • 生物物理

背景情况:

  • 质子合电子转移 (PCET) 是化学,生物学和物理学中的一个基本过程.
  • 已经开发了PCET的一般理论框架,包括电子和质子的量子力学效应,道化,环境重组和捐赠者-接受者波动.
  • 分析速率常数已被推导出用于各种模式,重点是振动性非反应模式.

研究的目的:

  • 提供一个关于计算PCET速率常数在振动性非adiabatic模式的输入量.
  • 详细计算内球和外球重组能量,二氧化质子潜力,电子合,反应自由能量和质子捐赠-接受器距离分布.
  • 为了指导对振动合的电子-质子非电性的确定.

主要方法:

  • 专注于黄金规则的速率常数表达,适用于振动式非反应式.
  • 用于PCET系统计算基本输入参数的详细说明.
  • 方法应用于各种系统,包括酶,同质分子电化学,光化学分子和异质电化学PCET.

主要成果:

  • 提供了计算PCET速率常数的全面指南.
  • 通过详细的例子展示理论表述的应用.
  • 介绍了公开可用的Python包,pyPCET,用于计算非adiabatic PCET速率常数.

结论:

  • 该教程为研究人员提供了计算PCET速率常数所需的工具和知识.
  • 通过pyPCET套件,可以将先进的理论方法应用于各种PCET系统.
  • 这项工作提高了跨学科复杂PCET流程的理解和计算可访问性.