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Updated: May 12, 2026

Cryosectioning of Contiguous Regions of a Single Mouse Skeletal Muscle for Gene Expression and Histological Analyses
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通过mRNA估计人类骨肌肉中的GAPDH和ACTB表达时间

Veena Devi1, Tulika Gupta1, Ujjwal Jit Kaur1

  • 1Department of Anatomy, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Clinical anatomy (New York, N.Y.)
|September 5, 2025
PubMed
概括

这项研究确定了甘甲基3-酸脱酶 (GAPDH) 和β-Actin (ACTB) mRNA作为估计死亡时间 (TSD) 的关键标记. 使用这些标记的数学模型在法医调查中提供了更高的准确性.

关键词:
核糖核酸降解法医病理学mRNA表达方式数学方程死亡后的变化自死亡以来的时间

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相关概念视频

Apoptosis01:30

Apoptosis

Apoptosis is a combination of two Greek words, 'apo' and 'ptosis,' meaning separation and falling off, respectively. Hippocrates used this word to describe gangrene, which was caused due to bandaging of fractured bones. Apoptosis was distinguished from necrosis in 1970 when John Kerr reported observations of morphological changes occurring during apoptosis. During one experiment, he observed that the disruption of blood supply to the liver tissue resulted in a size reduction of the tissue.