相关实验视频

Updated: Sep 8, 2025

Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles
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Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles

Published on: August 28, 2015

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基于聚氧乙烯 (POE) 的非离子表面活性剂的物理化学表征,用于单个和混合的细胞环境中增强抗癌药物的溶解

Virendra Prajapati1, Yashika Tomar2, Gautam Singhvi2

  • 1Department of Chemistry, Sardar Vallabhbhai National Institute of Technology (SVNIT), Ichchhanath Dumas Road, Keval Chowk, Surat-395007, Gujarat, India. ketankuperkar@gmail.com.

Physical chemistry chemical physics : PCCP
|September 5, 2025
PubMed
概括

这项研究使用Soluplus®和其他表面活性剂探索纳米细胞的形成,揭示了增强药物溶解和控制释放的协同效应. 这项研究强调Soluplus®

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Drug absorption within the gastrointestinal (GI) tract is a complex process influenced by several critical factors, including the site pH, the drug's dissociation constant (pKa), and the drug's lipophilicity. The GI tract exhibits a pH gradient, with an acidic environment in the stomach and a more alkaline environment in the small intestine. This pH variation directly affects the ionization state of drugs.
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