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Updated: Sep 8, 2025

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling
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神经再生的尖端技术

Chang-Ping Li1, Ying-Ying Wang1, Ching-Wei Zhou1

  • 1Center for Translational Neural Regeneration Research, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310016, China.

Cell regeneration (London, England)
|September 5, 2025
PubMed
概括

最近的生物技术进步,包括基因工程和人工智能,正在彻底改变中枢神经系统的神经再生. 这些技术为改善神经损伤的治疗和功能恢复提供了希望.

关键词:
三维细胞培养三维成像化学遗传学基因编辑神经再生视觉遗传学有机物单细胞测序

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Neurogenesis and Regeneration of Nervous Tissue01:15

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In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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