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Updated: Sep 8, 2025

Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source
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Published on: May 29, 2021

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通过虚拟选和初步打击优化识别Apo-Ido1抑制剂的新核心结构

Yekui Yin1,2,3, Meiqi He1,2,3, Jianda Yue1,2,3

  • 1The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha 410081 Hunan, China.

Journal of chemical information and modeling
|September 5, 2025
PubMed
概括

研究人员开发了一种虚拟查工作流程,以发现新型的胺二氧化酶1 (IDO1) 抑制剂. 这种方法确定了强大的apo-IDO1抑制剂,为癌症药物开发提供了有前途的策略.

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