与指南一致的癌症治疗成本的变化:观察和影响
Judy J Wang1, Sonia Persaud2, Sara Tabatabai3
1Department of Medicine, New York Presbyterian/Weill Cornell Medicine, New York, NY.
JCO oncology practice
|September 5, 2025
概括
由于新的生物标志物驱动疗法,癌症治疗指标的成本从2017年到2021年大幅增加. 仿制药或生物仿制药的进入使得一些治疗方法的成本大大降低.
科学领域:
- 癌症学
- 健康经济学
- 药物经济学
背景情况:
- 美国的癌症治疗费用很高.
- 之前的研究重点是药物定价, 而不是临床适应症.
- 符合指导方针的疗法对于最佳的患者结果至关重要.
研究的目的:
- 评估临床适应指南的癌症治疗的成本模式.
- 为了比较2017年和2021年的治疗费用.
- 确定癌症护理成本变化的驱动因素.
主要方法:
- 确定了国家综合癌症网络 (NCCN) 在2017年和2021年针对17种常见固体瘤的指导方针.
- 通过NCCN证据块得分确定可用的最佳治疗方法.
- 使用医疗保险报销率计算持续和每次疗程的费用.
主要成果:
- 持续治疗的中位成本从2017年的10,784美元增加到2021年的17,936美元.
- 每次疗程的中位成本从10,501美元 (2017) 降至9,038美元 (2021).
- 新药的中位成本较高;通用药/生物类似药的投入降低了57%的成本.
结论:
- 癌症治疗的绝对中位数成本增加了.
- 这种增长主要归因于新的生物标志物驱动的指示和疗法.
- 随着仿制药和生物类似药的可用性, 存在节省成本的机会.
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