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Updated: Sep 8, 2025

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中年女性患重度抑郁症的潜在风险生物标志物:嵌套病例对照研究

Xiao Wang1, Ashfaque A Memon1, Anna Hedelius1

  • 1Center for Primary Health Care Research, Lund University/Region Skåne, Malmö, 20502, Sweden.

Journal of affective disorders
|September 5, 2025
PubMed
概括

大脑衍生性神经营养因子 (BDNF) 的较高基线水平与中年妇女患重度抑郁症 (MDD) 的风险增加有关,这挑战了之前关于BDNF的假设.

关键词:
生物标志物大脑衍生的神经营养因子大型抑郁症风险预测

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Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
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